N-Alkylated 1,4-Dihydropyridines: New Agents to Overcome Multidrug Resistance.
نویسندگان
چکیده
منابع مشابه
Peroxisome Proliferator-Activated Receptors in Regulation of Cytochromes P450: New Way to Overcome Multidrug Resistance?
Embryonic and tumour cells are able to protect themselves against various harmful compounds. In human pathology, this phenomenon exists in the form of multidrug resistance (MDR) that significantly deteriorates success of anticancer treatment. Cytochromes P450 (CYPs) play one of the key roles in the xenobiotic metabolism. CYP expression could contribute to resistance of cancer cells to chemother...
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ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 1995
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.43.818